Mydriasis Causes & Treatment


As we discussed earlier, Mydriasis is a condition wherein the pupil is dilated and remains so for prolonged duration. There are two types of the condition: Unilateral or Bi-lateral. There many causes that are attributed to this condition, though only a few are listed herein. Few health conditions are also listed while other causes include drugs and trauma.

The most common causes include health conditions like Carotid artery aneurysm, Botulism, Adie's syndrome, Acute angle-closure glaucoma, Ocular surgery, Brain death, Raised intracranial pressure, Serotonin syndrome, Cerebral oedema and other causes like Antipsychotic agents, Cocaine, Lysergic acid diethylamide, Dopram Injection and lots more.

The most common drugs that are used to treat Mydriasis are Phenylephrine, Scopolamine and Murocol-2. They also suggest using eye protection until the condition is treated. However, seeking medical attention immediately is very important. Timely treatment goes a long way in curing or managing Mydriasis. The condition is often temporary, though becomes permanent due to improper treatment or ignorance often. Mydriasis that are due to health conditions and the outcome of treatment largely depend on the health condition itself.

Generally the affected individual, does not experience pain, though discomfort persists until the condition is cured.  There are few drugs that result in temporary Mydriasis, like for eg: eye drops used during a routine eye check-up. However, for all other related causes, a health specialist should be consulted. They suggest few tests and also analyze other symptoms, to determine the cause of the problem, to treat and eradicate it completely


  1. I have just returned from Emergency Room because my eye was dialated as big as my entire eye. I was in my garden cutting back a Trumpet Plant. When I went to cut a large section back a splash of liquid flew into my left eye. I ran into the house to wash my eye out, (Trumpet Plants are poisonious), anyway the doctor in E.R. said he had never come across anything like this before and said to me he would be right back that he was going to look up "Trumpet Plants". After an hour I told them I was leaving because I could look it up faster online myself and find out what to do, (which I wish I would have done in the first place.

  2. What are the causes of the pupil dilating in the opposite way i.e. the pupil getting smaller in dark light conditions. What are the causes, treatments and does it prevent driving in all conditions

  3. I am a nurse and I have a patient who has unilateral mydriasis.He said he has been to a different hospital and the doctors put some eyedrops "to have look at" his right eye.He came to us 2-3 days after, and his right eye still has mydriasis.He said he doent have any pain/discomfort in his eye, but has blurred vision.

    Should this be a concern?

    The doctors doesnt seem to be worried about this.

    NB-He is admitted with pnemonia and sepsis secondary to pneumonia.

  4. I had a corneal transplant 2 months ago and my pupil is still enlarged. Is this normal? any suggestions?

  5. Can you help me find a Dr.That treats Mydriasis in my area.(Coconut creek,Florida,33073) Thank You

  6. Thanks for this article. My granddaughter has large pupils all the time, does not use any drugs and has had a normal mri for her headaches. I will take her to an eye doctor. Thanks again.

  7. i had a tennis ball hit my left eye about 8 years ago and my pupil got dilate.

    it is getting worse to focus with both eyes.

    is there an specialized clinic to trat this?


  8. I put a drop of Atropine 1% o that caused my right eye to dialate, and later put a drop of Pred Forte 1% in the same eye because I was still having pain in the eye.

    I no longer have pain, but my eye has been dialated for two days.

    I cover my eyes with dark glases due to the sunlight.

    Do I need to see a doctor? When will my eye return to normal

    Help, Help, Help.

    I do not have the money to see a Specialist